Collaborations with SALSA

Collaborations with SALSA-SGC

With almost 10 years of data and samples collected, SALSA-SGC has built a strong resource for supporting MND researchers.

SALSA-SGC resources have been shared with a number of MND researchers, both in Australia and across the globe. Collaboration highlights include data linkage with the MINDAUS clinical registry here in Australia and contribution of genetic data to Project MINE. 

What resources does SALSA-SGC generate?

As part of the SALSA-SGC protocol, we collect clinical data, biological samples and generate genomic data. For participants with MND, clinical information and biological samples are collected every 3 months at regular MND clinic visits. Biological samples are subsequently processed and stored across three SALSA laboratories (QLD, NSW, WA). 

Clinical information

  • Onset of disease
  • Affected regions
  • Clinical phenotype
  • Disease progression (including ALSFRS-R scoring)
  • Treatments and interventions
  • Adaptive device and health resource utilisation
  • Clinical trial enrolment

Biological samples

  • Whole blood
  • Saliva
  • Plasma
  • Serum
  • Buffy coat
  • RNA expression
  • Extracted DNA
  • Extracted RNA

Genomics

  • Genome wide association scan
  • Genetic screening using a targeted neurodegenerative SNP panel
  • Whole genome sequencing
  • DNA methylation

Progress to date:

1044

cases recruited

1002

cases with clinical data

945

cases with biological samples

932

cases with genetic data

What's in the vault?

Explore our resources using the SALSA-SGC data explorer web app. Using this tool, you can dynamically query the SALSA-SGC collection to build custom cohorts/datasets. 

How to apply for data or samples?

Researchers can apply for access to SALSA-SGC data and/or samples via our online application form. Click the button below for further details.