Data Explorer Overview
The SALSA-SGC explorer is a dynamic web app built for exploring and querying the SALSA-SGC cohort, data, and samples. Use this tool to gain insights into the available resources within SALSA-SGC and build tailored cohorts for your research applications.
Please note that data and samples held at the Macquarie site are included in this tool, but the latest numbers and access to these samples/data must be arranged through the MQC site.
Interactive filtering
Apply interactive filters using the filter panel below. Click the reset button anytime to start over.
Visualise the results
See a dynamic update of the selected cohort at the bottom as you adjust filters.
Record your query
Click the save button to generate a unique query code and summary printout for your query.
Apply for data and/or samples
Complete the consortium request form on the main SALSA-SGC website, including your unique query code.
Filter Panel
Note: Filters applied here will update all plots below.
Current Selection
-
ALS Cases
-
Controls
-
Asymptomatic
-
Other
Available Resources
High-level overview of SALSA-SGC resources for selected cohort. Additional information is presented further below.
Participant Demographics
Age, gender, and ancestry across all participants.
Reported Ancestry
| - | European |
| - | Americas |
| - | Oceanian |
| - | A & TI |
| - | Asian |
| - | Middle Eastern |
| - | Other |
| - | Unknown |
MND Phenotype
Clinical phenotype and diagnostic criteria as captured at the most recent clinical visit.
Gold Coast Criteria
- meet criteria
El-Escorial Criteria
- Definite
- Probable
- Possible
MND Symptom Onset
Insights into age and region of symptom onset among MND cases.
Genetic Status
SALSA cases are routinely genotyped and screened for a range of ALS-associated variants.
| Genetic Variant | N Screened | N Positive |
|---|---|---|
| C9orf72 expansion | (%) | |
| SOD1 | (%) | |
| TARDBP | (%) | |
| FUS | (%) | |
| UNC13A rs12608932 (C/C) | (%) |
Available Resources
SALSA-SGC’s systems genomics approach generates multiple layers of data and samples for every MND case.
Longitudinal Resources for Cases
SALSA-SGC collects longitudinal data and samples for cases to facilitate biomarker and disease progression analyses.