What does participating in SALSA involve?
Our research aim
SALSA-SGC aims to build a national resource of data and biological samples that will support MND research projects today and moving into the future.
“Layers” of clinical, biological and genomic data will be generated to better understand the genetic and non-genetic factors that contribute to MND.
We will ask you to provide:
What will happen to my samples and data?
Biological samples are receipted at dedicated SALSA laboratories and processed into fractions (e.g. plasma).
Fractions are stored in secure freezers.
Lab staff routinely extract DNA and genotype samples. A variety of genomic data can be generated from these samples.
Analyses can be carried out using genomic data generated by the SALSA labs. All data is stored on secure platforms before, during and after analyses.
Frequently asked questions
- Genomics is the study of the genome.
- The genome is the DNA held in our chromosomes.
- Genomics includes study of the DNA sequence code.
- For any person the DNA sequence code is identical (almost exclusively) for all the cells in the body.
- Differences in DNA sequence between individuals can reflect, in part, differences between people in their risk of disease.
- The DNA sequence codes for genes. Specific proteins are made when genes are expressed.
- There are ~20,000 genes coded in the human genome.
- Genomics also includes the study of which, when, how and why genes are expressed, which differs between cells, over time, in response to environmental contexts and in response to disease.
- In systems genomics we measure different types of information from the genome from the same individuals to build up a picture of which, when, how and why genes are expressed in different cell types.
- Systems genomics is a new field, but one we think is going to become increasingly interesting for research.
We don’t know, but we believe that what we learn from genomics studies of sporadic ALS will help advance our understanding of the causes of ALS.
The consistent collection of biological and clinical samples implemented in clinics across Australia will contribute to many facets of clinical and non-genomics based research.
Have a question?
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